Miguel E. (Eduardo Miguel) emiguel@uemc.es

  • Bachelor of Science in Biochemistry. Faculty of Biology. University of Salamanca, Spain. 1995
  • Doctoral program in Molecular medicine. Dept. of Molecular Medicine. Faculty of Medicine. University of Salamanca, Spain. 1997-1999.
  • PhD in Biochemistry. University of Salamanca, Spain.
  • Professor at Miguel de Cervantes European University (Valladolid, Spain). Area of Cell Biology(since 2011)
  • Professor at Catholic University of Ávila (Ávila, Spain). Area of Cell Physiology. (since 2014)
  • Professor at Catholic University of Ávila (Ávila, Spain). Areas of Biochemistry, Nutrition and Pharmacology. 2014-2015.
  • Postdoctoral position (Contract). Dept. Biochemistry, Molecular Biology and Physiology. University of Valladolid, Spain. 2011-2012
  • Postdoctoral position (Contract). Spanish national program ‘Junta para la ampliación de estudios’. Posdoctoral (JAE-Doc). 2008-2011.
  • Postdoctoral position (Contract). Dept. Biochemistry, Molecular Biology and Physiology. University of Valladolid, Spain. 2007-2008.
  • Postdoctoral fellow. Dept. Biochemistry, Molecular Biology and Physiology. University of Valladolid, Spain. 2006.
  • Postdoctoral position (Contract). Biochemistry, Molecular Biology and Physiology. University of Valladolid, Spain. 2004-2006.
  • Postdoctoral fellow. Dept. Biochemistry, Molecular Biology and Physiology. University of Valladolid, Spain. 2003-2004
  • PhD student. Dept. Medicine. Faculty of Medicine. University of Salamanca. 1998-2000.
  • Contributor in the contract art.11 L.R.U. by Doctor Raquel Rodriguez Rodriguez with the company Farmahispania SA. Dept. Biochemistry and Molecular Biology. University of Salamanca. 1997-1998.
  • Graduate student (minor thesis). Dept. of Biochemistry and Molecular Biology. Faculty of Biology. University of Salamanca, Spain. 1995-1997.

‘Role of smooth muscle ion channels in vascular remodeling’. Ministerio de Ciencia e Innovación BFU2010-15898. P.I. Mª Teresa Pérez García.2011-2013.

‘Study of the mechanisms associated with Kv1.3 channel expression with human arterial tissue proliferation’. Junta de Castilla y León. Consejería de Educación. VA094A11-2. P.I. José Ramón López López. 2011-2013.

‘Network Heracles. Genetic and environmental determinants of vascular dysfunction in hypertension and ischemic heart disease’. Instituto de Salud Carlos III (SGEFI). RD06/0009/0013. P.I. José Ramón López López. 2007-2011

-‘Characterization of electrical remodeling of the vascular smooth muscle cells in an animal model of essential hypertension’. Proyecto de la DGI BFU2007-61524/BFI. P.I. José Ramón López López. 2007-2011.

-‘Hypoxia and vascular reactivity’. Junta de Castilla y León. Consejería de Educación. GR242. P.I. Constancio González. 2008-2010.

-‘Ion channelsandintimal proliferation. Characterization of thefunctionalroleof ion channelsintheprocessofphenotypic modulationofsmooth muscle cellsofthearterialwall’. FISS PI041044. P.I. José Ramón López López. 2004-2007.

-‘Role of voltage dependent potassium channels in the genesis of essential hypertension’. Proyecto de la DGICYT BFU2004-05551. P.I. Mª Teresa Pérez García. 2004-2007.

-‘Red Heracles. Genetic and environmental determinants of vascular dysfunction in ischemic heart disease and hypertension’. Instituto Carlos III (SGEFI). RED HERACLES (RD06/0009/0013). PI050155. P.I. José Ramón López López. 2005-2006.

-‘Genetic and environmentaldeterminantsof vascular dysfunctionin hypertensionandischemic heart disease’. Red del Instituto Carlos III G03/045. P.I. José Ramón López López. 2003-2006

-‘Characterizationofmolecular abnormalitiesin patients withsimple goiter’. Expediente nº 98/1359. Redes Temáticas FIS, Instituto de Salud Carlos III. P.I. José M. Miralles García. 1998-2000.

-‘Opioids Analogues Study’. Collaborating in the contract art.11 L.R.U. by Doctor Raquel Rodriguez Rodriguez with the company Farmahispania S.A. P.I. Raquel E. Rodriquez Rodriguez. 1997-1998.

  • C. Ruiz-McDavitt, E. Miguel-Velado, P Cidad, E. Alonso, J. López, M. Fernández, Y. Marroquín, J.R. López-López, M.T. Pérez-García       ‘Role of Kv1.3 And Kv1.5 in the Phenotypic Switch of Human Vascular Smooth Muscle Cells’. Poster. 4ª Reunión de la Red Española de Canales Iónicos (RECI IV). Cuenca (Spain), 2013.
  • Roque, M; Novensa, L; Cidad, P; Batlle, M; Miguel-Velado, E; Alonso, E; Perez-Garcia, T; Lopez, JR; Heras, M. ‘ROLE OF KV1.3 CHANNELS IN INTIMAL HYPERPLASIA’. Poster. 61st Annual Scientific Session and Expo of the American College of Cardiology (ACC). Chicago (USA), 2012
  • Sánchez García, A; Miguel-Velado, E; Gallego Sendín, S; García Sancho, J. ‘Análisis e interpretación de varias sobrecargas renales realizadas en alumnos de fisiología’. Oral comunication. XX Congreso de la Sociedad Española de Educación Médica. Valladolid (Spain), 2011.
  • Miguel-Velado E, Pérez-Carretero FD, Colinas O, Cidad P, Heras M, López-López JR and Pérez-García MT. Cell-Cycle Dependent Expression of Kv3.4 Channels Modulates Proliferation of Human Uterine Artery Smooth Muscle Cells.’ Oral comunication. 2ª Reunión de la Red Española de Canales Iónicos (RECI II). Valladolid (Spain), 2009
  • Pérez-García MT, Miguel-Velado E, Colinas O, Pérez-Carretero FD, López-López JR. ‘Proliferation of human uterine artery smooth muscle cells is regulated by cell cycle-dependent changes in the functional expression of Kv3.4 channels’. Oral communication. The FASEB Summer Research Conference (FASEB SRC). Lucca (Italy).
  • Miguel-Velado E, Colinas O, Pérez-Carretero FD, López-López JR and Pérez-García MT. ‘Cell cycle-dependent expression of Kv3.4 channels and cell proliferation in human uterine artery smooth muscle cells.’ Poster. Vascular & Smooth Muscle Physiology. The Physiological Society. King’s College. London, (UK), 2008.
  • Miguel-Velado E, Pérez-Carretero FD, Fernandez J, Garcia-Sancho FJ, Pérez-García MT, López-López JR. ‘A New Role of Kv3.4 Channels as Modulators of Proliferation, Migration and Cell Cycle Progression in Human Uterine Artery Smooth Muscle Cells’. Oral communication. XXXIV SECF Congress, Valladolid (Spain), 2007.
  • Miguel-Velado E, Moreno-Domínguez A, Pérez-García MT, López-López JR. ‘Phenotypic remodelling of Kv Channels expression in vascular smooth muscle cells from human uterine artery’. Poster. XXXIII Congress of the Spanish Society of Physiological Sciences. Sevilla (Spain), 2005.
  • Pérez-García MT, Käab S, Miguel-Velado E, López-López JR. ‘Remodelling of Kv Channels in Rabbit Carotid Body Chemoreceptor Cells by Chronic Hypoxia’. Oral communication. XXXIII Congress of the Spanish Society of Physiological Sciences. Sevilla (Spain), 2005.
  • Pérez-García MT, Miguel-Velado E, Moreno-Domínguez A, Olaia C, López-López JR. ‘Proliferation of human uterine artery SMCs modifies the expression profile of Kv channels’. Poster. XXXIII Physiological Society Meeting. Ion Channels, Genes and Regulation in Smooth Muscle. Oxford, (UK)
  • Pérez-García MT, Olaia C, Moreno-Domínguez A, Alonso E, Miguel-Velado E, López-López JR. ‘Hypoxic modulation of Kv channels in mouse carotid body chemoreceptor cells’. Poster. 48th annual meeting Biophysical Society. Baltimore (USA).
  • Rodriguez RE, Alvar F, Miguel-Velado E, Gonzalez-Sarmiento R. ‘Cloning and Characterization of a New TRKB Exon’. Poster. 48th Annual Meeting Society for Neuroscience. Los Angeles, California (USA) 1998.
  • Cidad P, Jimenez-Perez L, Garcia-Arribas D, Miguel-Velado E, Tajada S, Ruiz-McDavitt C, López-López JR, Pérez-García MT. (2012) Kv1.3 channels can modulate cell proliferation during phenotypic switch by an ion flux independent mechanism. Arterioscler Thromb Vasc Biol May; 32(5):1299-307.
  • Miguel-Velado E, Pérez-Carretero FD, Colinas O, Cidad P, Heras M, López-López JR, Pérez-García MT. (2010) Cell-cycle dependent expression of Kv3.4 channels modulates proliferation of human uterine artery smooth muscle cells. Cardiovascular Research 86: 383-391.
  • Moreno-Domínguez A, Cidad P, Miguel-Velado E, López-López JR, and Pérez-García MT (2009). De novo expression of Kv6.3 contributes to changes in vascular smooth muscle cell excitability in a hypertensive mice strain. The Journal of Physiology 587(Pt 3):625-40.
  • Miguel-Velado, E., Moreno-Domínguez, A., Colinas, O., Cidad, P., Heras, M., Pérez-García MT and López-López JR (2005). Contribution of Kv Channels to Phenotypic Remodeling of Human Uterine Artery Smooth Muscle Cells. Circulation Research 97(12),1280-7
  • Käab S, Miguel-Velado E, López-López JR and Pérez-García MT (2005) Downregulation of Kv3.4 channels by chronic hypoxia increases acute oxygen sensitivity in rabbit carotid body. Journal of Physiology 566: 395-408.
  • Ganfornina MD, Pérez-García MT, Gutierrez G, Miguel-Velado E, López-López JR, Marin A, Sánchez D, and Gonzalez C (2005) Comparative gene expression profile of mouse carotid body and adrenal medulla under physiological hypoxia . Journal of Physiology 566: 491-503.
  • Gonzalez-Sarmiento R, Corral J, Mories MT, Corrales JJ, Miguel-Velado E, Miralles-Garcia JM. (2001). Monoallelic deletion in the 5’ region of the thyroglobulin gene as a cause of sporadic nonendemic simple goiter. Thyroid 11(8): 789-93.

The major line of research is molecular biology.